LAMINATE / Longitudinal analysis

See the change
between sessions.

Compare a baseline and a follow-up session of the same subject. LAMINATE labels each lesion as new, growing, shrinking, static or gone, and reports lesion count, volume and the change in lesion load.

The lesion at baseline, circled in redThe same lesion at follow-up, circled in redBaselineFollow-up
The same lesion in the same plane, before and after. Drag to compare.

a real screen from LAMINATE

The LAMINATE Longitudinal Viewer showing the follow-up session with a growing lesion outlined in three planes, session statistics and keep or delete buttons
The Longitudinal Viewer: switch between Time 1 and Time 2, with each lesion’s status, the session statistics and your keep or delete decision.

What you bring

  • Two sessions of one subject: a baseline and a follow-up.
  • A FLAIR and a T1-weighted series in each session, as DICOM.
  • An uploaded archive, or both studies sent from your PACS in one upload.

What you get

  • Lesion segmentations for both sessions, registered to each other.
  • Each lesion labelled New, Growing, Shrinking, Static or Gone.
  • A report with lesion count, lesion volume, new lesion count and volume, expanding lesion volume and percent change in lesion load.
  • Lesion figures, and NIfTI volumes you can download.

What happens to a pair of sessions

  1. Align the sessions

    The baseline and follow-up images are registered to each other.

  2. Segment lesions

    Lesions are segmented in both sessions.

  3. Match and label

    In the viewer, lesions that overlap across the sessions are matched, so merges and splits are handled. Each lesion gets its status from the change in its volume.

  4. Report the change

    Measurements and figures are collected into a report you can view, download as HTML or save as PDF.

Review in the Longitudinal Viewer

  • Switch between baseline and follow-up with one key, or alternate them automatically.
  • Axial, sagittal and coronal views of both sessions, with crosshair, zoom and contrast.
  • A lesion list with each lesion’s status, volume and review progress. Jump to any lesion.
  • Keep or delete each lesion, which changes what the report counts.
  • Add a lesion the model missed, or redraw one. Clone a lesion’s shape between sessions, merge, or reset to the model output.
  • Edits save automatically, with undo, redo and a version history.
A LAMINATE report page showing one new lesion at baseline and at follow-up in axial, sagittal and coronal views, circled
The report shows each new lesion at baseline and at follow-up, in three planes.

what it does not do

Good to know

  • LAMINATE compares two sessions at a time. Each pair is its own analysis; trends across several visits are not available yet.
  • Both sessions must belong to the same subject, with FLAIR and T1-weighted images in each.
  • Results are NIfTI volumes, figures and a report. They are not returned to PACS as DICOM today.
  • An analysis starts automatically from PACS only when both studies arrive in one upload.

This application is intended for research and educational purposes only. It is not FDA-approved and should not be used for clinical diagnosis, treatment decisions, or patient care.

LAMINATE / Demo

Let’s explore your workflow.

Tell us a little about your team and we’ll shape the conversation around it. Please don’t include any patient information.

What would you like to explore?

An overview of the analysis and review experience.

Prefer to choose a time? Book a slot directly.